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When systemic glutathione levels are low, the resulting unchecked oxidative stress acts as a constant irritant to mast cells, keeping them in a hyper-reactive state

This evidence shows that lens epithelial cells are particularly susceptible to ferroptosis and sensitization during biologic processes related to aging

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[DOI] [PubMed] [Google Scholar] 35.Cuneo RC, Salomon F, Mcgauley GA, Sonksen PH