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Once the effects of the tripeptides were confirmed in U937 cells, the experiments were repeated in SH-SY5Y neuroblastoma cells and similar results were obtained ( Figure 4 )

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Both compounds require refrigeration for optimal stability, both are damaged by freezing, and both tolerate brief room temperature excursions

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Interactions between the melanocortin system and leptin in control of sympathetic nerve traffic

Even though these were diabetes trials, people lost between 8% and 14% of their weight, which tipped Lilly off that they had a massive weight-loss drug on their hands In general: the higher the dose, the higher the weight loss