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Its effects develop over time as the body gradually adjusts to the drug

With the Fenton reaction, both hydroxyl and peroxyl production can initiate the lipid peroxidation (Fig

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Together, current evidence shows that addictive drugs dysregulate multiple classes of ncRNAsincluding miRNAs, lncRNAs, and circRNAsin pathways that control synaptic plasticity, neuroinflammation, and reward-related transcription