Overall, the GF-MKD intervention was associated with modest , metabolite-specific changes rather than broad global metabolic remodeling, suggesting subtle metabolic modulation in ASD patients following dietary intervention
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The first is where the catechol-O-methyltransferase (COMT) enzyme, which helps degrade stimulatory compounds such as dopamine and adrenaline, does not work properly and lets these compounds accumulate in the nervous system