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Diabetes Obes Metab 17:219230 Adamis A et al (1994) Increased vascular endothelial growth-factor levels in the vitreous of eyes with proliferative diabetic-retinopathy

The derepressor factor is unknown (?), but the RNA binding proteins SPN-4 and MEX-5/6 are candidate components

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Morning dosing misses the acetaldehyde surge, which peaks 90 minutes after your last drink and triggers the inflammatory cascade (elevated IL-6, TNF-alpha) responsible for headache and nausea

For the vast majority of us, the rewards of improved blood sugar regulation far exceed the side effects