dsip peptide what is dsip (Delta Sleep-Inducing Peptide) DSIP | Peak Biosciences

The biological case rests on NAD+'s role as a substrate for three critical enzyme families: Sirtuins (SIRT1-7): These are longevity-associated proteins that regulate DNA repair, mitochondrial biogenesis, inflammation, and metabolic homeostasis

Mechanism: A synthetic tetrapeptide that activates telomerase, the enzyme responsible for extending telomeres, thereby promoting cellular longevity and delaying aging

One study shows that women who had lower than 250 mg/Dl levels of vitamin B12 were 3x more likely to give birth to a child with a birth defect than those who didnt

Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models

References: Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM

Tchkonia, H