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The rise of GLP-1 receptor agonists for use in type 2 diabetes Of the non-insulin treatments available for treating T2D, GLP-1 RAs offer the greatest reductions in HbA 1c , with more recent long-acting GLP-1 RAs matching, or even exceeding, glycaemic improvement achieved with basal insulin in T2D (Nauck et al, 2021)

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However, to further validate these results, the relationship between GLP-1 content and GLP-1R expression in response to liraglutide should be examined in future studies

3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes