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As the y-axis of the S-plot denotes confidence of a metabolites contribution to the group difference and the x-axis denotes the contribution of a particular metabolite to the group difference, the S-plot indicated the ion m/z 1175.6608 to show by far the highest difference in abundance in high producer strain WSBC 10925, whereas the ions m/z 453.2576 and m/z 837.4806 showed significantly higher abundance in the cereulide low-medium producer strain F3876/87 (Fig

Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody

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Epub 2015 Aug 9