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Following the ingestion of carbohydrates and fats, GLP-1 is released and exerts multiple physiological effects essential for maintaining glucose homeostasis ( Metabolically, GLP-1 acts through G protein-coupled receptors to improve insulin sensitivity in muscle and adipose tissues while enhancing -cell function by promoting proliferation and inhibiting apoptosis (see Figure 3)

Studies indicate that Tesamorelin can significantly reduce visceral fat

Its convenient liquid format supports laboratory studies involving intranasal peptide administration

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Our study aims to provide valuable real-world perspectives on the influence of GLP-1 RAs therapy among these patients

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