This ecological disruption is typically characterized by the reduction of beneficial bacteria such as Lactobacillus and Bifidobacterium , which play a protective role against pathogenic organisms [24, 36, 81]
In mice with DAT hypofunction, there were increased T regs in the thymus and spleen, reduced cyclo-oxygenase 2, TNF- , and Irf7 expression in microglia, and decreased monocyte infiltration into the brain
Swisher SG , Roth JA, Lawrence DD, Kemp BL, Carrasco CH, Fossella FV, Glisson BS, Hong WK, Khuri FR, Kurie JM, Nesbitt JC, Pisters KM, Putnam JB, Schrump DS, Shin DM, Walsh GL
Winkler EA, Bell RD, Zlokovic BV
All of which have been given to PCa patients
However, because this product provides doses far above the daily nutritional requirements (for instance 100 mg of B vs an RDA of ~1.4 mg), its use in pregnancy must be carefully considered