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Next, companies work on process development and scale-up, supported by Contract Development and Manufacturing Organizations (CDMOs) and academic collaborations

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In randomized controlled trials of semaglutide, participants lost on average 14.9-17.6% of their baseline weight over 68 weeks, according to a study cited in Statnews.com.(6) For the GLP-1 tirzepatide, average losses reached 21.4% at the highest studied dose over 72 weeks.(7) All groups in the controlled trials also received counseling on diet and exercise

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