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In this study, human umbilical vein endothelial cells (HUVECs), exposed to palmitic acid (PA) to induce endothelial dysfunction, were incubated with metformin, liraglutide or their combination
In all three neuronal clusters, we found a similar pattern of gene expression changes after treatment with the GIPR antagonist and acyl-GLP-1, with 29 genes in the C35 Glut10 cluster, 29 genes in the C35 GABA4 cluster and 45 genes in the C35 GABA3 cluster affected by both GLP-1R agonism and GIPR antagonism (Fig
Here we showed that the disruption of D2R-DAT interaction by TAT-DAT NT peptide stimulates locomotor behavior in normal and dopamine-depleted Sprague-Dawley rats by increasing extracellular dopamine, suggesting the TAT-DAT NT peptide might also exert beneficial effects in the animal model of ADHD
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