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Oral supplements are effective with doses starting at 2,000 mcg daily, followed by a decrease to 1,000 mcg daily, then weekly, and finally down to monthly

For LC, the mobile phase was composed of water and 0.1% formic acid (Solvent A) and acetonitrile and 0.1% formic acid (Solvent B)

Severe effects warrant immediate discontinuation

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It is an inert vehicle, so any adverse effects are usually related to the act of injection or the medication being administered rather than the diluent

Fourteen Participants A study reported shorter sleep-onset latency, less wakefulness after sleep onset and longer total sleep time following repeated intravenous exposure