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CE and NOR were part of the care team involved in daily discussions

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Testing homocysteine levels provides a practical way to assess the efficiency of the methylation cycle and identify individuals who may benefit from dietary or nutritional intervention

Statistical analysis A descriptive analysis was conducted for all the variables assessed at the index date, including age, sex, HbA 1c , educational level, and comorbidities

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therefore, improving lifestyle, reducing smoking, controlling weight, and providing psychological health guidance are treatment methods that target the specific pathogenesis of RA