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The G6PD5 proteoforms may recruit NADPH-dependent enzymes to ER subdomains Since among the pulled-down proteins, two cytochrome P450 enzymes (C4H/CYP73A5 and CYP71B6) were enriched as well (Figure 8D), we wondered whether the tendency of the membrane-bound G6PD5 proteoforms to cluster with the other two OPPP enzymes in ER subdomains may extend to enzymes of anabolic pathways that operate at the cytosolic face of the ER

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