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What it is / mechanism 5-Amino-1MQ is a selective, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that methylates nicotinamide (consuming the methyl donor SAM) to form 1-methylnicotinamide, diverting nicotinamide away from the NAD+ salvage pathway
The most common side effects in the first weeks are nausea, vomiting, and diarrhea, which usually improve after 2-3 weeks with consistent titration
Key cautions to keep in view Research status and evidence limits: Much of the mechanistic work is preclinical, and human data are limited
It is involved in the creation of blood cells, in the health of the neurological system, in the DNA of every cell in the body
The reconstituted solution should be clear and colorless
