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ROS can directly damage cellular macromolecules, including lipids, proteins, and DNA, leading to neuronal dysfunction and death [87]

Exogenous glucagon-like peptide 1 reduces contractions in human colon circular muscle

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J Biol Chem (1999) 274:3168692.10.1074/jbc.274.44.31686 122 LiJCulmanJHortnaglHZhaoYGerovaNTimmMet alAngiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury

This mechanism is why slow-release carbohydrates and prebiotic fibers are increasingly positioned to raise endogenous GLP-1 and PYY as a non-drug route to appetite regulation

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