The Next GLP-1 Wave: How Oral Launches Could Accelerate Utilization and Risk GLP-1 agents have reshaped the management of obesity, and the market continues to accelerate as new agents and indications emerge
However, emerging reports and legal filings have linked the use of GLP-1 receptor agonists to an increased risk of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE). While the drugs themselves are not blood thinners or thickeners in the traditional sense, the physiological changes they trigger in the body can create a "perfect storm" for clot formation
Proper site selection also involves considering factors such as skin integrity, previous injection sites, and individual patient anatomy
Note: If you experience severe, persistent abdominal pain that radiates to your back, stop the medication and contact a healthcare professional immediately, as this could be a sign of a more serious condition like pancreatitis
The glucagon component is the part that neither Mounjaro nor Wegovy has
Building on this earlier success , Amgens new Phase 2 trial lasted 52 weeks and enrolled patients living with obesity or both obesity and T2D