In addition to conducting tests on pitcher filters, under-sink filters, and the Big Berkey countertop system, Ive spoken extensively with filter engineers
Additionally, a rating of each study based upon the number of subjects studied, time interval of testing, dosing, technical parameters that were quantified, etc
The peptide upregulates tissue repair genes, downregulates inflammation genes, resets gene expression toward younger patterns, and activates stem cell markers (p63, integrins)
It also inhibits ferroptosis by lowering intracellular iron and ROS levels, increasing GPX4 expression, and reducing ACSL4
GSH and its oxidized form glutathione disulfide (GSSG) make up the most important thiol redox buffer in the body, and its homeostasis is critical to many important cellular functions
doi: 10.1186/s12974-022-02511-0 21 HouYWeiYLautrupSYangBWangYCordonnierSet al