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Ovaj peptidni segment prvobitno je izoliran iz prirodnog proteina u ljudskom eluanom soku - pepsinogen C (PGC), a nazvan je po znaajnim svojstvima zatite stanica i popravljanja tkiva

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Furthermore, GSTP1-1 has also been shown to bind and inhibit tumor necrosis factor receptor-associated factor 2 (TRAF2), an upstream activator of JNK, thus blocking the MAPK/JNK signaling cascade at multiple levels 29

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Tesofensine was originally developed for the treatment of Alzheimer's and Parkinson's