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Based on the data available in 2015, EFSA did not identify any known health risks associated with the use of dietary supplements, so no maximum dose or maximum daily intake, also known as a tolerable upper intake, was set (EFSA, 2015)

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Central Sensitization in Fibromyalgia A key aspect of fibromyalgia's chronic pain is its association with central sensitizationa condition where the central nervous system goes into a persistent state of high reactivity, amplifying pain signals

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