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We found that the glycolytic flux into the TCA cycle was reduced in Gclc fl/fl Mb1-Cre + FoB compared to Gclc fl/fl FoB, as indicated by increased M3-lactate and reduced M2-citrate (Supplementary Fig

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The control specifications for each test are as follows: vitamin B6 (plasma): Immundiagnostik/KC2100KO (CE-IVD certified) vitamin B9 (serum): Immundiagnostik/KIF005CTRL (CE-IVD certified) vitamin B12 (serum): Immundiagnostik/KIF012CTRL (CE-IVD certified) taurine (plasma): ERNDIM/AMI-02.1 and AMI-02.2 (ERNDIM IQCS) If necessary, repeated inspections and control testing were conducted

YS58 harboring the empty plasmid was employed as the control

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