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Clin Sci (Lond) 133(13):13671386

The amino acid sequence using standard one-letter codes with chemical modifications is: YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS Key chemical modifications: A : 2-aminoisobutyric acid (Aib) L : -methyl leucine (2-methylleucine) S : L-serinamide (carboxylic acid replaced with carboxamide) K : L-lysine with side chain (AEEA)-(-Glu)-(C20 diacid) Some peptides are synthesized with blocked N-termini, often modified with TFA salts, which can affect experimental outcomes such as cell growth and receptor activity due to residual TFA or chemical modifications at the N-terminus.The AEEA component represents 2-[2-(2-aminoethoxy)ethoxy]acetic acid, commonly used as a spacer group in synthetic peptides to enhance stability and receptor binding characteristics

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Vitamin A and Carotenoids - Fact Sheet for Consumers

Immediate medical attention is necessary if these symptoms occur

The stimulation of melanocortin receptors can cause melanin production