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These compounds are appealing due to their ability to work across multiple mechanisms (increased membrane disruption + increased antifungal uptake) and their potential to work in conjunction with standard antifungal medications

doi:10.1155/2022/2484018 73

chronic, maintenance of weight balance Synergy with leptin , amylin restores leptin sensitivity in obese models Synergy with CCK and GLP-1 , multi-pulse pathways of appetite suppression No tolerance , chronic administration of amylin preserves efficacy Why it matters: Lutzs review article established the scientific basis for amylin pharmacotherapy of obesity

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[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Higgins J.P., Liras G.N., Liras I.N

How myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) progresses: the natural history of ME/CFS