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Similarly erroneous are widely popularised views that reactive glia polarise into simple opposing functional states that are either good or bad, neuroprotective or neurotoxic, pro-inflammatory or anti-inflammatory, A1 or A2, and M1 or M2
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We worry about the drug causing hemolysis [the breakdown of red blood cells] in people who have congenital deficiency of G6PD, says Charles Abrams, MD, director of the Penn-CHOP Blood Center in Philadelphia
307 , H1754H1763 (2014)
Zhang Y, Guo Y, Zhang Q, Zhu Y, Xia Y, Wei Z, Dai Y
Substrate receptor proteins, such as von Hippel-Lindau tumor suppressor (VHL), suppressor of cytokine signaling (SOCS) (Figure 1) ( FIGURE 1 3 A unifying framework: the determinants of CUL5s context-dependent functions As the scaffold protein of the CRL5 complex ( 3.1 SOCS and CUL5 The SOCS protein family comprises eight members, which bind to Elongin B/C and recruit CUL5 to form CRL5 complexes
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