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2D) was 0.64 at 3 months, 0.32 at 6 months, 0.16 at 9 months, and 0.13 at 12 months in not treated subjects

doi: 10.1038/s41392-024-01931-z 26 NybergJJacobssonCAndersonMFErikssonPS

The extended 2030 hour half-life of IGF-1 LR3 means once-daily dosing maintains elevated IGF-1 receptor occupancy across multiple protein synthesis cycles, unlike native IGF-1s 10-minute half-life that requires frequent re-dosing

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Lancet Neurol 5(1):5363

Current heart failure reports