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10.1007/s11095-012-0958-3 51 KumarR.MondalK.PandaP

In line with these findings, in rats the activity of ADH was significantly reduced in diabetic models as well as in animals fed by high-carbohydrate, fat-free diet 100

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Longer-term use (6+ months) may create more durable improvements where enhanced dermal architecture supports ongoing collagen synthesis at rates intermediate between treatment peaks and pre-treatment baseline, potentially maintaining 40-60% of peak improvements indefinitely without continuous peptide application

This effect is dependent on phospholipase C activation and subsequent calcium release from IP 3 -sensitive intracellular stores [351]

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