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The main sites of copper accumulation are the liver and brain, leading to liver disease and neurological symptoms, which are the main features that lead to diagnosis[10]

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In another study, when comparing T1D C-peptide positive pre-pubertal children and adults vs their C-peptide negative counterparts, patients with a residual -cell function had higher IGF-I levels despite similar glycemic control (47, 48)

CK (1033 up-regulated genes and 712 down-regulated genes), and 2581 DEGs in K vs