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The third is linker leakage

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Spermatozoa possess primarily enzymatic antioxidants, with superoxide dismutase being the most predominant [54]

The natriuresis and the glycosuria-mediated osmotic diuresis caused by the SGLT2 inhibitors improve prognosis in HF by reducing plasma volume that leads to removal of interstitial fluid, thus reducing pulmonary congestion and oedema (Heerspink et al, 2018)

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