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There is no clinical evidence or regulatory endorsement to support extended dosing intervals, making any deviation from the prescribed weekly schedule an experimental approach with unknown risks and potential for reduced efficacy

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Lind M, Garcia-Rodriguez LA, Booth GL, Cea-Soriano L, Shah BR, Ekeroth G, Lipscombe LL: Mortality trends in patients with and without diabetes in Ontario, Canada and the UK from 1996 to 2009: a population-based study

You will lose some muscle along with fat

It is important to note that laxatives are not a solution for chronic constipation

Stomach (gastric) emptying is part of the digestive process wherein the foods and beverages we consume are moved from the stomach into the duodenum, the first part of the small intestine