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JAK inhibitors, as small-molecule drugs, block the tyrosine kinase activity of JAK family members, interrupt cytokine signaling, and inhibit downstream signals of pro-inflammatory cytokines, ultimately reducing intestinal inflammation [341, 347]

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Kraemer, J.S

Tirzepatide works best when combined with a healthy diet and regular exercise, so it is important to make these lifestyle changes to get the most benefit from the medication

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