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Studies (81, 82) have revealed that NOR can stably bind to AhR, promote AhR/Hsp90 dissociation and AhR nuclear translocation, increase the accumulation of AhR-ARNT complex, activate AhR-mediated reporter gene and up-regulate the expression of CYP1A1

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[DOI] [PubMed] [Google Scholar] 81.Marchese E., Rodeghier C., Monson R.S., McCracken B., Shi T., Schrock W., Martellotto J., Oberholzer J., Danielson K.K