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(4) Complex Ferroptosis involves multiple signaling pathways and molecular regulatory networks, including iron metabolism, lipid metabolism, antioxidant system, etc., which reflects the complexity of the ferroptosis pathway and provides a potential target for clinical intervention in related diseases ( Table 1 Overview of cell death types

The combination addresses both systemic inflammation and localized neural damage through complementary mechanisms

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Quantitect Reverse Transcriptase (RT) kits (Qiagen) were used to generate cDNA per kit instructions with control reactions performed without RT

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Normally, fibroblast activity declines dramatically with age