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There is considerable data to suggest that PEM suppresses the functioning of the acquired immune system

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For the duration of the study, animals were singly housed in standard individually ventilated cages (Innovive, San Diego, CA) with nesting material enrichment (ALPHA-Twist

In addition, liver autophagy defects have been shown to occur with several metabolic diseases, such as obesity, steatosis, and type 2 diabetes (Ueno and Komatsu, 2017)

Investigations propose that its interaction with pituitary cells might initiate signaling cascades involving phospholipase C, which could influence intracellular calcium release and protein kinase pathways

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