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10.1007/s12016-024-08991-7 207

Compared to liraglutide, semaglutide has an additional amino acid substitution in the 8th position from Ala to -aminobutyric acid (Aib) to avoid degradation by DPP-4 [64]

It does not introduce synthetic GH into the bloodstream directly

Thus, glutamine entry into the TCA cycle can provide metabolic intermediates for NRF2-regulated NADPH-producing enzymes, such as IDH1 and ME1

J Biol Chem (1991) 266:141558

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