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Morin hydrate overcomes this resistance by simultaneously inhibiting PARP1 and blocking protective autophagy, thereby synergistically enhancing cisplatins cytotoxicity

Ampk: Guardian of metabolism and mitochondrial homeostasis

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Sosa V, Moline T, Somoza R, Paciucci R, Kondoh H, Lleonart ME

For the cases in which genetic abnormalities have not been found it is very likely that MD is acquired

BMJ Case Rep 16:2015 Meleti M, Mooi WJ, Casparie MK et al (2007) Melanocytic nevi of the oral mucosano evidence of increased risk for oral malignant melanoma: an analysis of 119 cases