The counterargument is that subcutaneous delivery is more bioavailable than oral delivery, but even accounting for that difference, the dose is modest by any standard
That is double your starting dose, which may trigger significant gastrointestinal side effects including nausea, vomiting, and diarrhea
FDA Approves New Medication for Chronic Weight Management. FDA , 8 Nov
The table includes mean weight-loss percentage, approximate absolute weight loss (pounds), trial duration and the trial name
Propensity score matching Within each BMI subgroup, cohorts were matched 1:1 using nearest-neighbor propensity score matching without replacement
Studies show reduction of 12-15% of body weight in most patients on Semaglutide when combined with dietary changes and daily physical activity