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Lippincott-Raven, Philadelphia, pp 637669 Conrad, Sato H (2011) The oxidative stress-inducible cystine/glutamate antiporter, system x c : cystine supplier and beyond

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flooding the system beyond physiological buffering capacity just produces expensive urine

[21] In 2011, he was appointed as an Officer of the Order of Canada "for his contributions to the advancement of evidence-based medicine and its teaching." [22] [23] In 2012, he was elected a Fellow of the Royal Society of Canada

The aforementioned glutamine transporters are promising drug targets that can inhibit the uptake of glutamine by tumor cells from the source, block the nutritional and energy sources of tumor cells, and thus weaken the advantage of tumor cells in glutamine competition (Fig

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