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The consequences of Cd hitting mitochondria include oxidative stress, the production of ROS, the start of apoptosis, the mutation of MTs-DNA, the modification of gene expression, the inhibition of respiratory chain complexes, the reduction of ATP synthesis, and the modification of endo-mitochondrial conductivity

Its 12-month safety profile in long-term studies adds confidence for the extended treatment periods that TBI recovery demands

milder cognitive effects include various neurodevelopmental deficits, including intellectual impairment (66, 67)

PTP1B acts as a negative regulator of multiple receptor tyrosine kinases, including the EGFR