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Semaglutide, marketed as Ozempic, Wegovy, and Rybelsus, is an FDA-approved GLP-1 receptor agonist used to treat type 2 diabetes and manage chronic weight in adults with obesity

doi: 10.1007/s40519-022-01501-8 [DOI] [PubMed] [Google Scholar] 61.Lane MM, Lotfaliany M, Hodge AM, O'Neil A, Travica N, Jacka FN, et al

Additionally, naltrexone can precipitate withdrawal symptoms in patients with recent opioid exposure, a consideration independent of GLP-1 use but critical to assess before starting naltrexone