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The human body naturally secretes incretinsgut hormones that stimulate insulin secretion, regulate appetite, and alter energy balance

Conflicts of Interest: The authors declare no conflicts of interest

Another combines the GLP-1 drug semaglutide with a drug known as cagrilintide

GLP-1 signaling also antagonizes voltage-dependent K + (Kv) channels via cAMP/PKA-dependent pathway in beta cells, which prevents beta-cell repolarization by reducing Kv currents

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