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If the patient has an autoimmune disease or another condition that prevents the stomach from making intrinsic factor, then Vitamin B12 injections may be a better option
Another possibility is the following: after uptake, vitamin B12 is slowly bound to serum vitamin B12 proteins ( The mechanism by which vitamin B12 administration exerts its positive effect on ME/CFS patients is unknown
Consistent laboratory peptide handling may reduce variability and enhance reproducibility
Treatment with SOD mimetic (MnTMPyP) reduced the increased apoptosis sensitivity of CF cells, implicating superoxide-mediated oxidative stress (Rottner et al., 2011)
Samples were kept frozen prior analysis
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