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In the presence of OS in adipocytes, anti-inflammatory adiponectin level falls [118, 119], while pro-inflammatory adipocytokines concentration rises [115, 120, 121]

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Structural figures were prepared in UCSF Chimera 1.17.3, UCSF ChimeraX v1.0 and PyMOL 2.5.8 ( The final refinement statistics are provided in Table S1