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Moreover, most of the so far documented direct or indirect inhibitors of GPX4 may also affect other cellular processes not directly linked to ferroptosis induction leading to potentially detrimental side effects in patients

Hopkins et al., 2005), and may so act as a signal in the sulfate starvation regulatory network (Hirai et al., 2005

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Oxidized forms of glutathione in peripheral blood as biomarkers of oxidative stress

The levels of the iron-regulating protein TF are elevated in the retinas of monkeys and humans with glaucoma