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Similarly to glutamatergic synaptic transmission, activity-dependent functional changes in inhibitory neurotransmission are accompanied by alterations in GABAergic synapse structure that range from morphological reorganization of postsynaptic density to de novo formation and elimination of inhibitory contacts
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Additionally, inhibition of PKC was shown to reduce NRF2 phosphorylation and transcriptional activity, along with the expression and activity of NRF2-regulated antioxidant proteins [43]
It is an investigational compound presented here for research and educational purposes only and is not approved for general human use
