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This metabolism pathway via CYP450, specifically cytochrome P450 2E1 (CYP2E1), produces reactive oxygen species[17], originally thought to be the ultimate cause of liver injury in paracetamol overdose

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Selenium Selenium (Se) is an essential trace element for humans and animals, serving as the main component of many antioxidant proteins in the body, such as thioredoxin reductase, selenoprotein P and GPX