For individuals who often feel fatigued or lethargic, these injections can provide a much-needed boost
It helps regulate blood sugar by: Stimulating insulin release after eating Slowing down gastric emptying (which makes you feel fuller for longer) Reducing appetite by signalling satiety to the brain Pharmaceutical GLP-1 medications amplify these effects, which is why theyre used for managing blood sugar and supporting weight management
For the PLB-treated group, mice were additionally injected intraperitoneally with PLB (10 mg/kg/day) for 20 days
Image Credit: Edugrafo / Shutterstock In a recent comprehensive network meta-analysis published in the journal Translational Psychiatry , researchers evaluated the safety and effectiveness of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for individuals with mental illness and comorbid obesity or overweight-related metabolic risk
This notion was recently confirmed by identification of the Pdcd4 target, stress-activated-protein kinase interacting protein 1 (Sin1), whose translation is inhibited by Pdcd4 through suppressing eIF4A activity
Shdaifat EA, Abu Sneineh FT, Ibrahim AM