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The peptide activates HGF/c-Met signaling cascades that upregulate synaptogenesis, dendritic spine growth, and NMDA receptor expression, and these changes continue autonomously once triggered

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MS3 precursors were fragmented by HCD and analyzed using the Orbitrap (collision energy 55%, AGC 1.5E5, maximum injection time 120 ms, resolution was 50,000)

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis