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PsO and PsA are notably associated with increased concentrations of inflammatory cytokines, including tumor necrosis factor (TNF), interferon (IFN)-, interleukin (IL)-17, IL-22, and IL-23, in both skin and synovial tissues

The STEP 8 trial by Rubino et al

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One six-month, randomized, double-blinded, placebo-controlled trial found that taking oral glutathione at either 250 or 1,000 mg/day led to significant increases in the body stores of glutathione in a dose-dependent manner

Diabetes 45 , 13791385 (1996)