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Its levels vary throughout the body, reaching up to 10 mM in liver cells while other cells maintain millimolar concentrations

& Schultz, G

And they did a comparison of 1000mg a day of EPA

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Allergic reactions, though rare, can also occur

For example, opioids decrease pulmonary perfusion via hypoxia-induced pulmonary vasoconstriction 143 , and by direct pulmonary vasoconstriction 144,145 by mechanisms including centrally-mediated activation of sympathetic nerve activity to the lungs 146 , and induction of histamine release in the lungs 144,147